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CDC HIV/AIDS/Viral Hepatitis/STD/TB Prevention News Update

Briefings: Testing for HIV in Urine


Science (07/13/90) Vol. 249, No. 4965, P. 121

Several companies, including Abbott Laboratories, DuPont, Wellcome Diagnostics, and Calypte Biomedical, have produced new tests to screen for HIV in urine that would make the procedure much easier, especially for developing countries with scarce medical facilities. The tests screen for HIV in urine, eliminating the need for trained medical personnel who can draw blood. None of the tests has won approval from the Food and Drug Administration, but data presented at the Sixth International Conference on AIDS appeared promising. Wellcome's test kit was the least reliable, with 14 false positives from 325 negatives and 37 false negatives from 452 positives. Abbott's test fared better, finding 4 false positives in 236 negative samples and 26 false negatives in 330 positive samples. Calypte's test had 7 false positives from 931 low-risk samples and no false negatives, making it the best candidate. A successful urine test could be incorporated into an HIV home test kit, according to Calypte president Howard Urnovitz.


Copyright © 1990 -CDC Prevention News Update, Publisher. All rights reserved to Information, Inc., Bethesda, MD. The CDC National Center for HIV, STD and TB Prevention provides the following information as a public service only. Providing synopses of key scientific articles and lay media reports on HIV/AIDS, other sexually transmitted diseases and tuberculosis does not constitute CDC endorsement. This daily update also includes information from CDC and other government agencies, such as background on Morbidity and Mortality Weekly Report (MMWR) articles, fact sheets, press releases and announcements. Reproduction of this text is encouraged; however, copies may not be sold, and the CDC HIV/STD/TB Prevention News Update should be cited as the source of the information. Contact the sources of the articles abstracted below for full texts of the articles.

Information in this article was accurate in July 13, 1990. The state of the art may have changed since the publication date. This material is designed to support, not replace, the relationship that exists between you and your doctor. Always discuss treatment options with a doctor who specializes in treating HIV.