life-threatening complication of sputum induction

CDC HIV/AIDS/Viral Hepatitis/STD/TB Prevention News Update Life-Threatening Complication of Sputum Induction Nelson, M., et al.
January 13, 1990

Lancet (01/13/90) Vol. 335, No. 8681, P. 112 M. Nelson and colleagues from Westminster Hospital, London, recommend caution with sputum induction used to diagnose Pneumocystis carinii pneumonia in patients with AIDS. Nelson and colleagues report four deaths in patients with small pleural effusions; two also had widespread cutaneous Kaposi's sarcoma. Nausea and coughing are the only reported side-effects of this procedure, they write, but the four patients who died experienced a rapid increase in the volume of pre-existing pleural effusions.

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