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CDC HIV/AIDS/Viral Hepatitis/STD/TB Prevention News Update

MAC (MAI) Treatment Trial at NIH: Sparfloxacin, Azithromycin


AIDS Treatment News (06/05/92) No. 152, P. 7

AIDS patients with MAC bacteremia who are in a relatively stable condition and able to travel to the National Institutes of Health in Bethesda, Md., may qualify for a trail which randomly assigns sparfloxacin, azithromycin, or the combination of these drugs for MAC treatment. All participants receive oral medication with no placebo involved in the trial. Study visits will be weekly for one month, every two weeks for the next eight weeks, and then monthly. Participants will be monitored as long as possible. In addition, those who fail any treatment arm may obtain a four-drug combination consisting of sparfloxacin, azithromycin, clofazimine, and ethambutol. Part of the purpose of the study is to test this method.


Copyright © 1992 -CDC Prevention News Update, Publisher. All rights reserved to Information, Inc., Bethesda, MD. The CDC National Center for HIV, STD and TB Prevention provides the following information as a public service only. Providing synopses of key scientific articles and lay media reports on HIV/AIDS, other sexually transmitted diseases and tuberculosis does not constitute CDC endorsement. This daily update also includes information from CDC and other government agencies, such as background on Morbidity and Mortality Weekly Report (MMWR) articles, fact sheets, press releases and announcements. Reproduction of this text is encouraged; however, copies may not be sold, and the CDC HIV/STD/TB Prevention News Update should be cited as the source of the information. Contact the sources of the articles abstracted below for full texts of the articles.

Information in this article was accurate in June 5, 1992. The state of the art may have changed since the publication date. This material is designed to support, not replace, the relationship that exists between you and your doctor. Always discuss treatment options with a doctor who specializes in treating HIV.