high virological rate of hiv protease inhibitors reported

CDC HIV/AIDS/Viral Hepatitis/STD/TB Prevention News Update High Virological Rate of HIV Protease Inhibitors Reported
November 19, 1997

Reuters Health Information Services (11/19/97) New research published in the November 15 issue of AIDS suggests that there is a high virological failure rate associated with the use of HIV protease inhibitors. Scientists from the University of Cologne in Germany report a 44 percent virological treatment failure rate in a study of 198 HIV-positive patients treated with protease inhibitors. The findings suggest that the success seen in controlled studies is not necessarily reflected in everyday practice, the researchers noted. Further study, they said, should investigate optimal initial therapy and optimal therapeutic sequences for both untreated and pretreated individuals.

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Copyright © 1997 -CDC Prevention News Update, Publisher. All rights reserved to Information, Inc., Bethesda, MD. The CDC National Center for HIV, STD and TB Prevention provides the following information as a public service only. Providing synopses of key scientific articles and lay media reports on HIV/AIDS, other sexually transmitted diseases and tuberculosis does not constitute CDC endorsement. This daily update also includes information from CDC and other government agencies, such as background on Morbidity and Mortality Weekly Report (MMWR) articles, fact sheets, press releases and announcements. Reproduction of this text is encouraged; however, copies may not be sold, and the CDC HIV/STD/TB Prevention News Update should be cited as the source of the information. Contact the sources of the articles abstracted below for full texts of the articles. Information in this article was accurate in November 19, 1997. The state of the art may have changed since the publication date. This material is designed to support, not replace, the relationship that exists between you and your doctor. Always discuss treatment options with a doctor who specializes in treating HIV.