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CDC HIV/AIDS/Viral Hepatitis/STD/TB Prevention News Update

Relevance of AIDS Treatment With Two Nucleoside Analogues


Lancet (06/12/99) Vol. 353, No. 9169, P. 1989

New research regarding the use of zidovudine alone or in combination with didanosine or zalcitabine offers useful data on treatment with two nucleoside analogue drugs to extending survival and slowing HIV progression, write researchers in a Lancet commentary. The researchers--from the Centers for Disease Control and Prevention, the Uganda Cancer Institute, and Projet RETRO-CI--note that there are costs and benefits for both the patient and the community in antiretroviral therapy. However, the more important issues in many countries include programs' lack of ability to monitor therapy; diagnose and treat opportunistic infections; control tuberculosis; and prevent secondary HIV-1 transmission, among others. The authors assert that, while critical, "the issue of antiretrovirals must not supersede the fundamental need to raise the standard of care for all AIDS patients."


Copyright © 1999 -CDC Prevention News Update, Publisher. All rights reserved to Information, Inc., Bethesda, MD. The CDC National Center for HIV, STD and TB Prevention provides the following information as a public service only. Providing synopses of key scientific articles and lay media reports on HIV/AIDS, other sexually transmitted diseases and tuberculosis does not constitute CDC endorsement. This daily update also includes information from CDC and other government agencies, such as background on Morbidity and Mortality Weekly Report (MMWR) articles, fact sheets, press releases and announcements. Reproduction of this text is encouraged; however, copies may not be sold, and the CDC HIV/STD/TB Prevention News Update should be cited as the source of the information. Contact the sources of the articles abstracted below for full texts of the articles.

Information in this article was accurate in June 16, 1999. The state of the art may have changed since the publication date. This material is designed to support, not replace, the relationship that exists between you and your doctor. Always discuss treatment options with a doctor who specializes in treating HIV.