Gac Med Mex. 1999 Nov-Dec;135(6):669-75. Unique Identifier : AIDSLINE
OBJECTIVE: To describe the clinical and epidemiological features of
severe acute poisonings in an adult population. DESIGN: Retrospective
analysis of clinical cases. PATIENTS AND METHODS: Analysis of the
clinical charts, risk factors and main outcomes of 55 acute poisoned
patients admitted to an intensive care unit (ICU). RESULTS: Of the 55
clinical charts reviewed, female prevailed over male gender with a
relation of 1.5:1, the average age was 32 years (16-83 years), the major
etiologic factor for the acute poisonings were drugs in 35 cases (64%),
and home or work chemicals in 20 cases (36%). The mechanisms of
intoxication/poisoning were: attempted or successful suicide in 51 cases
(93%), accidental poisoning in three cases (5%), and iatrogenic in one
case (2%). Precipitating factors were major depressive disorder in 29
cases (53%), dysthymic disorder in 12 cases (22%) and adjustment
disorder with depressive mood or impulsive act in nine cases (16%).
Associated feature comorbid conditions were: homosexuality,
schizophrenia, drug addiction, AIDS, other chronic diseases, and
previous suicide attempts. Outcomes were 33 (60%) patients discharged
from the ICU without sequela, seven (13%) with permanent severe sequela
and 15 (27%) deaths. CONCLUSIONS: There was a high rate of suicides
related with depressive disorders in a predominantly female population.
Drug products were used more frequently than home or work chemicals.
Although advanced life support and antidotal treatments were available,
mortality was high. Areas where injury prevention efforts might have an
influence on adult poisoning morbidity and mortality include management
of depression as well suitable control of drugs and chemicals.
JOURNAL ARTICLE graves en una poblacion adulta que ingresa a una unidad
de cuidados intensivos. Acute Disease Adolescence Adult Age Factors
Aged Aged, 80 and over Comparative Study English Abstract Female
Human Intensive Care Units Male Mexico/EPIDEMIOLOGY Middle Age
Poisoning/*EPIDEMIOLOGY/PSYCHOLOGY Risk Factors Sex Factors
Suicide/PSYCHOLOGY/*STATISTICS & NUMER DATA Suicide,
Attempted/PSYCHOLOGY/STATISTICS & NUMER DATA