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Fat redistribution in HIV disease.




 

J Am Acad Dermatol. 2000 May;42(5 Pt 1):727-30. Unique Identifier :

BACKGROUND: Abnormal distributions of body fat have been reported in association with HIV infection, including cases of both regional loss and gain of fat. OBJECTIVE: We describe the spectrum of abnormal fat distribution in HIV-positive patients. METHODS: Patients were included if they demonstrated a lack of subcutaneous fat in the cheeks in the absence of generalized wasting. Patients were examined fully and photographed, and medical records were reviewed. RESULTS: Fourteen patients were seen. Further abnormalities of body fat distribution were noted in all patients. We found a consistent pattern of fat loss in the cheeks, temples, and extremities as well as fat gain over the neck, upper back, mastoid processes, chest, and visceral abdomen. CONCLUSION: A consistent syndrome of body fat redistribution is seen in HIV-positive patients. A characteristic pattern of fat loss in the cheeks may serve as a specific marker of HIV-related fat redistribution.

JOURNAL ARTICLE Adipose Tissue/*PHYSIOPATHOLOGY Adult Anti-HIV Agents/THERAPEUTIC USE Blood Glucose/ANALYSIS Human HIV Infections/BLOOD/DRUG THERAPY/*PHYSIOPATHOLOGY HIV Seropositivity/PHYSIOPATHOLOGY Lipids/BLOOD Male Middle Age



 




Information in this article was accurate in July 30, 2000. The state of the art may have changed since the publication date. This material is designed to support, not replace, the relationship that exists between you and your doctor. Always discuss treatment options with a doctor who specializes in treating HIV.