Ann Med Interne (Paris). 2000 Jun;151(4):291-6. Unique Identifier :
Antiretroviral drugs exhibit significant between-patient pharmacokinetic
variability. Over the past years, data have emerged demonstrating a link
between antiretroviral drug concentrations and efficacy or side-effects.
As a result, the issue of therapeutic drug monitoring for these
compounds are arisen; many published studies provided evidence that
plasma concentrations contributes to therapeutic response. However,
further information must be collected to define more precisely the
therapeutic concentrations and the indications of therapeutic
drug-monitoring for each drug.
JOURNAL ARTICLE REVIEW REVIEW, TUTORIAL antiretroviraux dans la prise
en charge des patients infectes par le virus de l'immunodeficience
humaine. Anti-HIV Agents/*BLOOD/PHARMACOKINETICS/THERAPEUTIC USE
Dose-Response Relationship, Drug Drug Monitoring/*METHODS English
Abstract Human HIV Infections/*BLOOD/*DRUG THERAPY Patient Selection