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[The value of plasma antiretroviral drug monitoring in the management of HIV infected patients]


Ann Med Interne (Paris). 2000 Jun;151(4):291-6. Unique Identifier :

Antiretroviral drugs exhibit significant between-patient pharmacokinetic variability. Over the past years, data have emerged demonstrating a link between antiretroviral drug concentrations and efficacy or side-effects. As a result, the issue of therapeutic drug monitoring for these compounds are arisen; many published studies provided evidence that plasma concentrations contributes to therapeutic response. However, further information must be collected to define more precisely the therapeutic concentrations and the indications of therapeutic drug-monitoring for each drug.

JOURNAL ARTICLE REVIEW REVIEW, TUTORIAL antiretroviraux dans la prise en charge des patients infectes par le virus de l'immunodeficience humaine. Anti-HIV Agents/*BLOOD/PHARMACOKINETICS/THERAPEUTIC USE Dose-Response Relationship, Drug Drug Monitoring/*METHODS English Abstract Human HIV Infections/*BLOOD/*DRUG THERAPY Patient Selection Treatment Outcome


Information in this article was accurate in December 30, 2000. The state of the art may have changed since the publication date. This material is designed to support, not replace, the relationship that exists between you and your doctor. Always discuss treatment options with a doctor who specializes in treating HIV.