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[Mother-to-child transmission of HIV infections. Antiviral agents and Cesarean section reduce the risk of transmission]


Lakartidningen. 2000 Jul 12;97(28-29):3275-9. Unique Identifier :

There has been a substantial decrease in maternal-infant transmission of HIV in many European and North American countries during the past five years, from 15-25 per cent to approximately 5%. Reasons include the prophylactic administration of zidovudine to mother and child, more effective treatment strategies leading to decreased viral load during pregnancy, and increased use of elective Caesarean section. In developing countries however, the vertical transmission rate of HIV is still high at 25-40 per cent. Simpler and less expensive prophylactic regimens, such as nevirapine to mother and child at delivery and after birth, respectively, have raised hope. Drug resistance and the risk of adverse effects of antiretroviral drugs on the child are threats to the prevention of mother-to-infant transmission of HIV.

JOURNAL ARTICLE minskar risk for smitta. Anti-HIV Agents/*ADMINISTRATION & DOSAGE/ADVERSE EFFECTS *Cesarean Section Comparative Study Developed Countries Developing Countries Disease Transmission, Vertical/*PREVENTION & CONTROL Drug Resistance, Microbial English Abstract Female Human HIV Infections/PREVENTION & CONTROL/*TRANSMISSION Infant, Newborn Maternal-Fetal Exchange Practice Guidelines Pregnancy Pregnancy Complications, Infectious/DRUG THERAPY Risk Factors Zidovudine/*ADMINISTRATION & DOSAGE


Information in this article was accurate in December 30, 2000. The state of the art may have changed since the publication date. This material is designed to support, not replace, the relationship that exists between you and your doctor. Always discuss treatment options with a doctor who specializes in treating HIV.