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Human T-cell lymphotropic virus type III (HTLV-III) embryopathy. A new dysmorphic syndrome associated with intrauterine HTLV-III infection.


Am J Dis Child. 1986 Jul;140(7):638-40. Unique Identifier : AIDSLINE

Twenty infants and children with positive serologic tests for the human T-cell lymphotropic virus type III (HTLV-III) were noted to have similar features including growth failure (75%), microcephaly (70%), and craniofacial abnormalities consisting of ocular hypertelorism (50%); prominent box-like appearance of the forehead (75%); flat nasal bridge (70%); mild upward or downward obliquity of the eyes (65%); long palpebral fissures with blue sclerae (60%); short nose with flattened columella and well-formed, triangular philtrum (65%); and patulous lips (60%). These features constitute a new and distinct dysmorphic syndrome, the HTLV-III embryopathy.

Acquired Immunodeficiency Syndrome/*CONGENITAL/COMPLICATIONS Anthropometry Antibodies, Viral/*ANALYSIS Child, Preschool Facial Bones/*ABNORMALITIES Female Fetal Diseases/*MICROBIOLOGY Fetal Growth Retardation/ETIOLOGY Growth Disorders/ETIOLOGY Human HTLV-BLV Viruses/IMMUNOLOGY Infant Male Pregnancy Retroviridae Infections/*MICROBIOLOGY Skull/*ABNORMALITIES Support, Non-U.S. Gov't Support, U.S. Gov't, P.H.S. JOURNAL ARTICLE


Information in this article was accurate in September 30, 1986. The state of the art may have changed since the publication date. This material is designed to support, not replace, the relationship that exists between you and your doctor. Always discuss treatment options with a doctor who specializes in treating HIV.