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Primary central nervous system lymphoma related to Epstein-Barr virus in a patient with acquired immune deficiency syndrome.


Ann Neurol. 1986 Jul;20(1):98-102. Unique Identifier : AIDSLINE

The study of a patient suggested a relationship between Epstein-Barr virus infection and primary lymphoma of the central nervous system in the acquired immune deficiency syndrome. Deoxyribonucleic acid preparations from tumor tissue contained 30 to 100 copies of Epstein-Barr virus genome per cell when hybridized with a probe consisting of the Bam-HI K fragment of Epstein-Barr virus strain FF41. This hybridization study suggests that induction of this patient's central nervous system lymphoma was related to Epstein-Barr virus infection.

Acquired Immunodeficiency Syndrome/*COMPLICATIONS Brain Neoplasms/ANALYSIS/*COMPLICATIONS Case Report DNA, Viral/ANALYSIS Herpesvirus 4, Human Human Lymphoma, Non-Hodgkin's/ANALYSIS/*COMPLICATIONS Male Middle Age *Occipital Lobe Tumor Virus Infections/*COMPLICATIONS JOURNAL ARTICLE


Information in this article was accurate in November 30, 1986. The state of the art may have changed since the publication date. This material is designed to support, not replace, the relationship that exists between you and your doctor. Always discuss treatment options with a doctor who specializes in treating HIV.