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The effect of a cetylpyridinium chloride (CPC) detergent foam compared to a conventional toothpaste on plaque and gingivitis. A single blind crossover study.


J Clin Periodontol. 1989 Feb;16(2):87-91. Unique Identifier : AIDSLINE

A CPC-detergent formulation in a foam vehicle, was compared with a fluoride toothpaste for its ability to prevent plaque and gingivitis over a period of 12 days. Whilst refraining from all other oral hygiene procedures, the foam or toothpaste was applied to the teeth in fluoride application trays, in a group of 14 volunteers. At days 8 and 12 of this crossover study, the following assessments were made: gingival crevicular fluid; gingival index; bleeding on probing; plaque index; plaque area. Except for plaque area at day 8 of the study, there were no significant differences between the 2 products at either day 8 or day 12. It is therefore concluded that the CPC-detergent formulation, in its present form, does not inhibit plaque and gingivitis more effectively than a conventional fluoride toothpaste.

Adolescence Adult Cetylpyridinium/*THERAPEUTIC USE Comparative Study Dental Plaque/*PREVENTION & CONTROL Dental Plaque Index *Dentifrices Female Fluorides/*THERAPEUTIC USE Gingival Crevicular Fluid Gingivitis/*PREVENTION & CONTROL Human Male Periodontal Index Pharmaceutic Aids Phosphates/THERAPEUTIC USE Pyridinium Compounds/*THERAPEUTIC USE Sodium Fluoride/THERAPEUTIC USE *Toothpaste JOURNAL ARTICLE


Information in this article was accurate in June 30, 1989. The state of the art may have changed since the publication date. This material is designed to support, not replace, the relationship that exists between you and your doctor. Always discuss treatment options with a doctor who specializes in treating HIV.