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Polarization and capping of lymphocytes in HIV infection.


Microbiologica. 1990 Apr;13(2):131-5. Unique Identifier : AIDSLINE

The present study was undertaken to assess the locomotor capacity of lymphocytes from patients with human immunodeficiency virus (HIV) infection by a polarization assay. In addition, the capping phenomenon of lymphocytes from HIV-infected patients or in vitro preincubation of lymphocytes with HIV-envelope glycoproteins, gp41 and gp120 was evaluated. A significant decrease in polarized lymphocytes from patients with acquired immunodeficiency syndrome (AIDS) was observed. On the other hand, the capping phenomenon either of lymphocytes from AIDS patients or of lymphocytes from healthy donors preincubated with gp41 and gp120 was reduced but not significantly.

Chemotaxis, Leukocyte Human HIV Envelope Protein gp120/PHARMACOLOGY HIV Envelope Protein gp41/PHARMACOLOGY HIV Infections/*IMMUNOLOGY *Immunologic Capping Lymphocytes/*IMMUNOLOGY/PHYSIOLOGY JOURNAL ARTICLE


Information in this article was accurate in September 30, 1990. The state of the art may have changed since the publication date. This material is designed to support, not replace, the relationship that exists between you and your doctor. Always discuss treatment options with a doctor who specializes in treating HIV.