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Opportunistic infections and malignancies in 231 Danish AIDS patients.


AIDS. 1990 Mar;4(3):233-8. Unique Identifier : AIDSLINE MED/90274898

We analysed cumulative disease frequencies in the first 231 adult Danish AIDS patients with life tables. There was a certain hierarchical pattern in the occurrence of complicating diseases. Herpes zoster, Kaposi's sarcoma and Pneumocystis carinii pneumonia were early manifestations, whereas diseases caused by cytomegalovirus and atypical mycobacteria tended to occur later in the course of AIDS. Compared with all other AIDS patients, homosexual men were more likely to develop Kaposi's sarcoma, cytomegalovirus chorioretinitis and mucocutaneous herpes simplex virus infection. The proportion of patients who developed particular diseases changed with calendar time. Most striking was a three to fourfold decrease in diseases caused by cytomegalovirus. In conclusion, the study showed that disease frequencies in patients with AIDS may vary with the patients risk behaviour and duration of AIDS, and that the frequencies of particular diseases may change with calendar time.

Acquired Immunodeficiency Syndrome/*COMPLICATIONS/EPIDEMIOLOGY Adult Denmark/EPIDEMIOLOGY Female Human Male Neoplasms/*COMPLICATIONS Opportunistic Infections/*COMPLICATIONS Pneumonia, Pneumocystis carinii/COMPLICATIONS Risk Factors Support, Non-U.S. Gov't Time Factors JOURNAL ARTICLE


Information in this article was accurate in September 30, 1990. The state of the art may have changed since the publication date. This material is designed to support, not replace, the relationship that exists between you and your doctor. Always discuss treatment options with a doctor who specializes in treating HIV.