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HIV infection in intravenous drug users in Berlin (West): risk factors and time trends.


Int Conf AIDS. 1990 Jun 20-23;6(2):445 (abstract no. 3173). Unique

OBJECTIVE: To determine risk factors for HIV infection and to study time trends of HIV seroprevalence in intravenous drug users (IVDU) in Berlin (West). METHODS: From 1984 to 1989 784 heterosexual IVDU were recruited anonymously from facilities for drug treatment and counselling. Serological tests were carried out for HIV, hepatitis A and B, lues and toxoplasmosis. Data on social and behavioural features were collected. RESULTS: 23.2% were seropositive for HIV. Seroprevalence rates of hepatitis B, hepatitis A and lues were 67.1%, 39.5%, and 3.9%, respectively. HIV seropositivity was significantly associated with sharing of injection equipment, imprisonment and intravenous drug use in prison. The crude time trend of HIV seroprevalence (concerning the year of the last iv drug use) shows an increase from 17.9% in 1983 to 29.1% in 1985, and decreases to 17.2% in 1988. The estimated HIV seroprevalence odds, adjusted for temporal changes in the study group, show an increasing trend over the last years. CONCLUSIONS: The increase in the adjusted HIV seroprevalence odds suggests that continued efforts are necessary to reduce the spread of HIV among IVDA in Berlin (West). As more detailed data indicate, IVDU of young age and in prison should be main target groups for AIDS prevention.

Berlin/EPIDEMIOLOGY Hepatitis A/EPIDEMIOLOGY Hepatitis B/EPIDEMIOLOGY Human HIV Infections/*EPIDEMIOLOGY Risk Factors *Substance Abuse, Intravenous Time Factors Toxoplasmosis/EPIDEMIOLOGY ABSTRACT


Information in this article was accurate in December 30, 1990. The state of the art may have changed since the publication date. This material is designed to support, not replace, the relationship that exists between you and your doctor. Always discuss treatment options with a doctor who specializes in treating HIV.