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HIV serology in Mexican blood banks: the quality control program of the Centro Nacional de la Transfusion Sanguinea.


Int Conf AIDS. 1990 Jun 20-23;6(2):428 (abstract no. 3107). Unique

OBJECTIVE: To verify the proficiency of Governmental blood banks laboratories screening donors for HIV-1 antibody, in the middle of 1989, an external quality program was initiated, sending a sera panel with known reactivity, twice a year to 207 blood banks. METHODS: With a serum of a single donor, positive for HIV-1 antibody, 3 dilutions were prepared: 1-strongly, 2-moderately and 3-weakly repeatedly reactives. In addition, we sent 4 negative sera. Results were reported to the CNTS for evaluation. RESULTS: We have received at the moment 156 reports (75.4%). False negatives with strongly reactive sera-1 (0.5%). False negatives with moderately reactive sera-8 (3.9%). False negatives with weakly reactive sera-12 (5.8%). False positives with negative sera-7 (3.4%). CONCLUSION: Reagents for screening of HIV antibody presently used in Mexico seem to perform adequately. False negative in strongly reactive sera, as well as 2 false negatives with the moderately reactive sera were due to clerical error, increasing the number of false positives. We conclude that efforts should be directed to improve laboratory organization in order to avoid clerical errors.

*Blood Donors False Negative Reactions False Positive Reactions Human HIV Antibodies/*BLOOD HIV Infections/*EPIDEMIOLOGY HIV-1/IMMUNOLOGY Mass Screening Mexico/EPIDEMIOLOGY ABSTRACT


Information in this article was accurate in December 30, 1990. The state of the art may have changed since the publication date. This material is designed to support, not replace, the relationship that exists between you and your doctor. Always discuss treatment options with a doctor who specializes in treating HIV.