Hematol Oncol Clin North Am. 1991 Apr;5(2):297-310. Unique Identifier :
Kaposi's sarcoma (KS) is the most common malignancy seen in association
with AIDS. Important epidemiologic trends in the occurrence of
AIDS-associated Kaposi's sarcoma (AIDS-KS) have been identified, and the
molecular processes associated with the development of KS are being
studied intensively. It is hoped that these studies will ultimately lead
to an understanding of the etiology of the disease and to a rational
approach to therapy. Treatment with conventional chemotherapy, radiation
therapy, biologic therapy, and various local treatment modalities is
effective for palliation of clinical problems associated with AIDS-KS,
although the toxicities of these approaches may be problematic. Therapy
for AIDS-KS must be individualized, with appropriate consideration given
to the patient's overall clinical and immunologic status.
Acquired Immunodeficiency Syndrome/*COMPLICATIONS Human Sarcoma,
Kaposi's/*DRUG THERAPY/ETIOLOGY/PATHOLOGY Support, Non-U.S. Gov't
JOURNAL ARTICLE REVIEW REVIEW, TUTORIAL