J Environ Pathol Toxicol Oncol. 1990 Nov-Dec;10(6):326-30. Unique
The lymphoma occurring in AIDS patients is characterized by the
following features. 1. It is a B-cell malignant neoplasm of high-grade
malignancy resulting from a profound T-cell suppression caused by the
cytotoxic effect of a retrovirus that has lymphotropism for the T4
subset. 2. The age of lymphoma patients parallels that of AIDS patients.
3. Prodromal manifestations frequently herald the emergence of the
lymphoma. 4. Extranodal involvement is frequently seen. 5. The lymphomas
are resistant to treatment, with low patient survival.
Acquired Immunodeficiency Syndrome/*COMPLICATIONS/EPIDEMIOLOGY Human
Lymphoma/*ETIOLOGY/THERAPY JOURNAL ARTICLE REVIEW REVIEW, TUTORIAL