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Fiberoptic bronchoscopic diagnosis of pulmonary disease in 151 HIV-infected patients with pneumonitis.


Eur J Clin Microbiol Infect Dis. 1991 Jun;10(6):491-6. Unique Identifier

In a prospective study the efficacy of fiberoptic bronchoscopy was evaluated in the diagnosis of infections with opportunistic pathogens, Kaposi's sarcoma and nonspecific interstitial pneumonitis in 171 episodes of pneumonitis in 151 HIV-infected patients. Samples were collected by suction through the inner aspiration channel of the bronchoscope (n = 164), telescoping plugged catheter (n = 117) and transbronchial lung biopsy (n = 82). A high incidence of infections with pyogenic bacteria (12%), Legionella spp. (5 %) and Mycobacterium tuberculosis were diagnosed (9%). Bronchoalveolar lavage demonstrated a high diagnostic rate in bacterial pneumonia (significance level greater than 10(5) cfu/ml) and a low degree (10%) of contamination (less than 1% squamous epithelial cells). Bronchoalveolar lavage was more effective than the telescoping plugged catheter in yielding a significant number of colonies in patients with bacterial pneumonia previously treated with antibiotics. Nondiagnosed pneumonitis was more frequent in intravenous drug abusers than in homosexual men (p less than 0.001).

Adult Bacterial Infections/COMPLICATIONS/DIAGNOSIS Bronchoalveolar Lavage Fluid/MICROBIOLOGY Bronchoscopy Cytomegalovirus Infections/COMPLICATIONS/DIAGNOSIS Female Fiber Optics Homosexuality Human HIV Infections/*COMPLICATIONS Lung Diseases, Fungal/COMPLICATIONS/DIAGNOSIS Male Middle Age Opportunistic Infections/COMPLICATIONS/*DIAGNOSIS Pneumonia, Pneumocystis carinii/COMPLICATIONS/DIAGNOSIS Prospective Studies Pulmonary Fibrosis/COMPLICATIONS/*DIAGNOSIS Sarcoma, Kaposi's/COMPLICATIONS/*DIAGNOSIS Substance Abuse, Intravenous/COMPLICATIONS Support, Non-U.S. Gov't JOURNAL ARTICLE


Information in this article was accurate in January 30, 1992. The state of the art may have changed since the publication date. This material is designed to support, not replace, the relationship that exists between you and your doctor. Always discuss treatment options with a doctor who specializes in treating HIV.