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High prevalence of human papillomavirus and cervical intraepithelial neoplasia in a young Australian STD population.


Int J STD AIDS. 1991 Jul-Aug;2(4):276-9. Unique Identifier : AIDSLINE

Two hundred and forty-five women consecutively attending a large city Sexually Transmitted Diseases (STD) Centre had routine cervical screening performed by both the Pap smear and, in addition, a Cervigram. The aim of this study was to determine the prevalence of HPV infection, CIN and cervical cancer in an STD population. The mean age of this group was 26 years with a range from 16 to 53 years. Colposcopy and biopsy revealed a prevalence for human papillomavirus (HPV) of 41%, and 20.4% for cervical intraepithelial neoplasia (CIN). No cases of cervical cancer were detected. The Pap smear detected HPV-associated change in 18% and CIN in 8.2%, therefore generally underestimating the true prevalence of HPV and CIN. Cervicography was positive in 44% of the total group, indicating either HPV-associated change or CIN. Current screening methods are therefore failing to detect significant amounts of HPV-associated change and CIN.

Adolescence Adult Ambulatory Care Facilities Biopsy/STANDARDS Cervix Diseases/DIAGNOSIS/*EPIDEMIOLOGY/PATHOLOGY Cervix Dysplasia/DIAGNOSIS/*EPIDEMIOLOGY/PATHOLOGY Cervix Neoplasms/DIAGNOSIS/*EPIDEMIOLOGY/PATHOLOGY Colposcopy/STANDARDS Female Human Mass Screening/STANDARDS Middle Age New South Wales/EPIDEMIOLOGY *Papillomavirus Photography/STANDARDS Prevalence Sensitivity and Specificity Support, Non-U.S. Gov't Tumor Virus Infections/DIAGNOSIS/*EPIDEMIOLOGY/PATHOLOGY Vaginal Smears/STANDARDS JOURNAL ARTICLE


Information in this article was accurate in January 30, 1992. The state of the art may have changed since the publication date. This material is designed to support, not replace, the relationship that exists between you and your doctor. Always discuss treatment options with a doctor who specializes in treating HIV.