J Clin Ultrasound. 1991 Oct;19(8):485-92. Unique Identifier : AIDSLINE
Adult T-cell leukemia/lymphoma (ATLL) is an HTLV-I associated lymphoid
malignancy frequently seen in Japan. Abdominal involvement in 40
patients with ATLL were assessed by ultrasonography and the findings
seen in four clinical types, acute, chronic, lymphoma and smoldering,
were compared. Splenomegaly was frequently found in the cases of acute
and lymphoma types, and the sizes of the spleens measured by
ultrasonography correlated well with the disease activity. Hepatomegaly
was also found more frequently in acute and lymphoma types, and
hepatosplenomegaly was proved to be due to the infiltration by ATL
cells. Nodular lesions in spleen and liver and abdominal lymph node
swelling were also found frequently in the lymphoma type but rarely in
the other types. Ascites, pleural effusion, and pericardial effusion
were found in the active stage of acute and lymphoma types.
Ultransonography also could detect findings associated with therapies.
Thus, ultrasonography studies were found to be very useful for assessing
the clinical classification, examining various pathological conditions
associated with ATLL, and monitoring the disease activity.
Abdominal Neoplasms/*ULTRASONOGRAPHY Comparative Study Female
Hepatomegaly/ETIOLOGY/ULTRASONOGRAPHY Human Leukemia-Lymphoma, T-Cell,
Acute, HTLV-I-Associated/ *ULTRASONOGRAPHY Male Middle Age
Splenomegaly/ETIOLOGY/ULTRASONOGRAPHY JOURNAL ARTICLE