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Tuberculosis in HIV seropositive individuals--a retrospective analysis.


Int J STD AIDS. 1992 Jan-Feb;3(1):38-41. Unique Identifier : AIDSLINE

A retrospective analysis of all culture-positive cases of Mycobacterium tuberculosis infection in HIV positive individuals, over a 5 year period, revealed 18 cases, drawn from a population of approximately 1500. The prevalence of culture proven M. tuberculosis over the 5 year period was therefore 1.2% and was strongly associated with either a concomitant, or a subsequent, AIDS diagnosis. Sixty-one per cent had pulmonary tuberculosis, 17% had both extra-pulmonary and pulmonary infection and 22% had extra-pulmonary infection alone. Although a wide range of radiological abnormalities was seen, segmental consolidation was the commonest, occurring in 57% of cases. Only 55% of the specimens were positive on initial stains for M. tuberculosis, with a mean duration of 4 weeks to become culture positive, emphasizing that early diagnosis rests on clinical suspicion.

Adult Cause of Death Human HIV Seropositivity/*COMPLICATIONS/EPIDEMIOLOGY London/EPIDEMIOLOGY Middle Age Prevalence Retrospective Studies Risk Factors Thoracic Radiography Time Factors Tuberculosis/DIAGNOSIS/*EPIDEMIOLOGY/MICROBIOLOGY JOURNAL ARTICLE


Information in this article was accurate in June 30, 1992. The state of the art may have changed since the publication date. This material is designed to support, not replace, the relationship that exists between you and your doctor. Always discuss treatment options with a doctor who specializes in treating HIV.