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Cognitive deficits associated with human immunodeficiency virus encephalopathy.


J Neuropsychiatry Clin Neurosci. 1990 Summer;2(3):256-60. Unique

The encephalopathy associated with direct nervous system infection by the human immunodeficiency virus (HIV) has been recognized as one of the major debilitating aspects of the acquired immunodeficiency syndrome (AIDS) and of pre-AIDS conditions. A comprehensive neuropsychological examination of symptomatic HIV-infected subjects without opportunistic cerebral disease demonstrated a distinctive pattern of cognitive deficits marked by prominent attentional impairment. Evidence of organizational and reasoning impairments also was observed, but language, visual-spatial, and memory consolidation abilities were relatively preserved. The findings suggest a profile of impairment similar to other cognitive syndromes involving dysfunction of predominantly anterior brain structures and projections and suggest a rationale for psychostimulant drug treatment.

Adult Attention AIDS Dementia Complex/*DIAGNOSIS/PSYCHOLOGY Bisexuality/PSYCHOLOGY Cognition Disorders/*DIAGNOSIS/PSYCHOLOGY Homosexuality/PSYCHOLOGY Human Male *Neuropsychological Tests Orientation Psychomotor Performance Recall JOURNAL ARTICLE


Information in this article was accurate in October 30, 1992. The state of the art may have changed since the publication date. This material is designed to support, not replace, the relationship that exists between you and your doctor. Always discuss treatment options with a doctor who specializes in treating HIV.