Int Conf AIDS. 1992 Jul 19-24;8(1):Th69 (abstract no. ThC 1522). Unique
OBJECTIVE: to determine the influence of breast-feeding on
HIV-seroprevalence among newborns of HIV-infected mothers. METHODS: All
the examined HIV(+) women which had delivery after May 1988 were
suggested to wean their infants. RESULTS: Among 32 observed
'mother-child' pairs 2 children died in perinatal period, 2--emigrated,
28--were enrolled in the survey. 5 children under 12 months of age are
still being followed up. Among 23 pairs 6 children were breast-fed,
17--bottle-fed. Out of those 17 bottle-fed, 16 infants were found HIV(-)
in 12 months, 1--HIV(+) at the age of 15 months (P = 0.021). 5 of the 6
breast-fed were confirmed sero(+), being known that 2 got infected via
breastfeeding as their mothers had been infected via hemotransfusion
after delivery (P = 0.089). The 6th breast-fed was found sero(-), the
duration of his breast-feeding was only 1 month. Thus,
HIV-seroprevalence among bottle-fed newborns was significantly less than
in those which were breast-fed by their mothers prior to May 1988 (p
less than 0.05). CONCLUSIONS: We believe our investigation has revealed
that breast-feeding presents a high risk for maternal-infant HIV-
transmission. Bottle-feeding may be suggested as a preventive measure
for HIV-seroprevalence among children.
Blood Transfusion/ADVERSE EFFECTS Bottle Feeding Breast Feeding
Female Human HIV Infections/*PREVENTION & CONTROL/TRANSMISSION HIV
Seropositivity/TRANSMISSION Infant Infant, Newborn Pregnancy Weaning
ABSTRACT