Resource Logo

[HTLV-I and ocular disease]


Nippon Ganka Gakkai Zasshi. 1993 Apr;97(4):433-40. Unique Identifier :

Human T-lymphotropic virus type 1 (HTLV-I) has an etiologic role in adult T-cell leukemia (ATL) and HTLV-I associated myelopathy (HAM). This paper reviews the ophthalmic literature relevant to the retrovirus. Patients with ATL may have intraocular invasion of proliferated T lymphocytes, lymphomatous lesion in the ocular adnexa, or cytomegalovirus retinitis due to immunocompromisation. Patients with the chronic neurological disease HAM may present with retinal vasculitis, isolated cotton-wool spots, probably immune-mediated uveitis, and/or retinochoroidal degenerative change. Similar retinal vascular or uveal inflammatory disease is occasionally seen in otherwise healthy HTLV-I carriers. Clinical and epidemiologic data suggest the existence of HTLV-I associated uveitis (HAU) that is assumed to be associated with the retrovirus. Further ophthalmic research is encouraged to elucidate the clinical significance of the worldwide HTLV-I infection.

Carrier State/EPIDEMIOLOGY English Abstract *Eye Infections, Viral/EPIDEMIOLOGY Female Human HIV *HTLV-I Infections/EPIDEMIOLOGY Male Paraparesis, Tropical Spastic Support, Non-U.S. Gov't JOURNAL ARTICLE REVIEW REVIEW, TUTORIAL


Information in this article was accurate in September 30, 1993. The state of the art may have changed since the publication date. This material is designed to support, not replace, the relationship that exists between you and your doctor. Always discuss treatment options with a doctor who specializes in treating HIV.