Int Conf AIDS. 1993 Jun 6-11;9(1):303 (abstract no. PO-B04-1006). Unique
Specific opportunistic infections among HIV positive persons often
cluster in specific geographic area and risk group concerned. Unlike
other parts of India the epidemic of HIV is mainly concentrated among
IDUs in Manipur, a state bordering Myanmar. It is estimated that there
will be approximate 10,000 HIV +ve IDUs between 15-35 yr in the State
where the epidemic has started in 1990. Fifty percent of the IDUs are
positive for HIV and account for largest number of clinical cases in
India at present. This study presents the positive predictive value of
different clinical signs and symptoms among HIV +ve IDUs. Seventy-five
HIV +ve and -ve age matched IDU, registered for a clinical cohort study
were followed for one year. Clinical examination and supportive
laboratory investigations were carried out for all possible
opportunistic infection. The result shows that in comparison with the
HIV -ve individual Herpes Zoster had a positive predictive value of 100%
for HIV condition. The same rate was respectively 88.4%, 70%, 75%, and
98%, for cervical lymphadenopathy, wt loss < 10%, wt loss > 10% and
pruritus of unknown aetiology. Recently there has been two fold rise of
Herpes Zoster cases among 15-35 yrs of patients attending the hospital
O.P.D. in the state capital. The details will be presented.
*AIDS-Related Opportunistic Infections/EPIDEMIOLOGY *Herpes
Zoster/COMPLICATIONS *Herpes Zoster/EPIDEMIOLOGY *Substance Abuse,
Intravenous/COMPLICATIONS