Int Conf AIDS. 1993 Jun 6-11;9(1):284 (abstract no. PO-B01-0897). Unique
OBJECTIVE: To determine the relationship between the levels of amylase
and triglycerides with the clinical stage and the CD4 cell counts.
METHODS: 146 HIV+ patients were studied with serum amylase and
triglycerides and CD4 cell counts. We made two groups: IVDU and no IVDU,
we classified the patients by CDC staging system (1986): stage 1 (II,
III), stage 2 (IVA, IVC2), stage 3 (case definition for AIDS, CDC 1987).
We excluded patients with history of pancreatitis or prior therapy with
pentamidine, DDI or DDC. Statistical analysis: analysis of variance,
Student's t-test. RESULTS: 110 men and 36 women. IVDU 71%, no IVDU 29%.
Stage 1 67, stage 2 40, stage 3 39. There were not differences for age,
sex or risk group between the groups. Women had amylasemias higher (mean
204) than men (mean 134) P = 0.07. TABULAR DATA, SEE ABSTRACT VOLUME.
CONCLUSIONS: 1) Unexplained elevations of serum amylase are related to
advanced HIV infection and CD4 cell depletion. 2) The hyperamylasemia is
more elevated in women without relation with age or group risk. 3)
Hyperamylasemia without pancreatic clinical disease probably non refuse
absolutely drugs potentially causing pancreatitis. 4)
Hypertriglyceridemia is frequent in advanced HIV infection and its
relation with wasting should be investigated.
*Amylases/BLOOD *Hypertriglyceridemia/COMPLICATIONS *HIV