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Disseminated bacillary angiomatosis in AIDS patients.


Int Conf AIDS. 1994 Aug 7-12;10(2):141 (abstract no. PB0578). Unique

OBJECTIVES: Description of clinical and therapeutic characteristics of an uncommon pathology in HIV-infected patients: Disseminated Bacillary Angiomatosis, in 4 AIDS patients. METHODS: Evaluation of 4 AIDS patients with Disseminated Bacillary Angiomatosis, registered at the Institute of Infectology Emilio Ribas. Diagnosis was obtained by biopsy of skin lesions and Whartin-Starry staining in all patients. RESULTS: From the 4 patients: 3 were homosexuals men and 1 heterosexual woman. The mean age was 32 years (range 22 to 40 years old). Two patients had a previous diagnosis of AIDS, one of them had Pulmonary tuberculosis as opportunist infection, and the other Lymph node tuberculosis and Corioretinitis by CMV. The other two patients had bacillary angiomatosis as the first opportunist infection. All of them had persistent fever previously of the appearance of skin lesions. The lesions were characterized by a multiform form, with maculae, papules and nodules, sometimes confluents. Some of them complain of local pain. Two patients with more disseminated lesions had oral infiltration. They had anemia and leukopenia. The histopathology was characteristic at Whartin-Starry staining revealed clusters of bacilli in all cases. Hemoculture was negative. IGM and IgG anti-Rochalimae was detected in one patient. Erythromycin in usual dosage was the drug used and there was prompt remission of the lesions, but in one case, the lesions reappeared after 4 months. CONCLUSIONS: Bacillary Angiomatosis is not a common disease in HIV infected individuals, it may be present as the first opportunist infection. The disseminated cases generally occurred in patients with advanced immunossupresion.

Adult *Angiomatosis, Bacillary/DIAGNOSIS/THERAPY *AIDS-Related Opportunistic Infections/DIAGNOSIS/THERAPY Female Human Male ABSTRACT


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