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NLM AIDSLINE

The immunoactivetherapy for patients with positive HIV using glycyrrhizin.




 

Int Conf AIDS. 1994 Aug 7-12;10(1):218 (abstract no. PB0302). Unique

OBJECTIVE: Six hemophiliacs with positive HIV treated with glycyrrhizin for 11 years. METHODS: The effects were described as the changes of 1) absolute lymphocyte counts; 2) CD4 counts; 3) CD8 counts and 4) CD4/CD8 ratio. Of course, complete blood counts, liver function, determination of immunoglobulin and etc. were examined. 400 ml (800 units) of glycyrrhizin/day was infused every day. RESULTS: Absolute lymphocytes, CD4 and CD4/CD8 ratio elevated in all patients. 4 patients have good qualities of life now. In addition, glycyrrhizin could relief the bone marrow suppression as a side effect of AZT. DISCUSSION AND CONCLUSIONS: The administration of glycyrrhizin was considered to be effective to prevent the development to AIDS.

Acquired Immunodeficiency Syndrome/PREVENTION & CONTROL Adjuvants, Immunologic/*THERAPEUTIC USE Bone Marrow Diseases/CHEMICALLY INDUCED/THERAPY CD4-CD8 Ratio CD4-Positive T-Lymphocytes Glycyrrhetinic Acid/*ANALOGS & DERIVATIVES/THERAPEUTIC USE Hemophilia/COMPLICATIONS Human HIV Infections/COMPLICATIONS/*THERAPY Leukocyte Count Quality of Life T-Lymphocytes, Cytotoxic Treatment Outcome Zidovudine/ADVERSE EFFECTS ABSTRACT



 




Information in this article was accurate in December 30, 1994. The state of the art may have changed since the publication date. This material is designed to support, not replace, the relationship that exists between you and your doctor. Always discuss treatment options with a doctor who specializes in treating HIV.