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[Cerebro-meningeal infections in patients with human immunodeficiency virus infections]


Rev Prat. 1994 Oct 15;44(16):2187-94. Unique Identifier : AIDSLINE

Opportunistic infections of the central nervous system, frequent in AIDS, present essentially in 4 clinical pictures: brain mass lesion(s), meningitis, diffuse encephalitis or prolonged fever. Toxoplasmosis is by far the most frequent cause of brain mass lesion. Therefore, for patients presenting with a brain mass lesion it is recommended to start presumptive antitoxoplasmic therapy with the combination of pyrimethamine and sulfadiazine. Other etiologies (lymphoma and progressive multifocal leukoencephalopathy) should be considered only after failure of this treatment. The other infectious processes are much more uncommon (cryptococcoma, tuberculoma, Candida, Nocardia abscesses). In case of meningitis, cryptococcosis must be searched for, in addition to classic causes of meningitis. Diffuse febrile encephalitis should lead to consider presumptive antitoxoplasmic therapy. Finally, prolonged fever can be the only expression of cerebral toxoplasmosis or cryptococcal meningitis.

AIDS-Related Opportunistic Infections/*ETIOLOGY/THERAPY Bacterial Infections/COMPLICATIONS/THERAPY Central Nervous System Diseases/*ETIOLOGY/THERAPY English Abstract Human HIV Infections/*COMPLICATIONS Mycoses/COMPLICATIONS/THERAPY Parasitic Diseases/COMPLICATIONS/THERAPY Virus Diseases/COMPLICATIONS/THERAPY JOURNAL ARTICLE


Information in this article was accurate in March 30, 1995. The state of the art may have changed since the publication date. This material is designed to support, not replace, the relationship that exists between you and your doctor. Always discuss treatment options with a doctor who specializes in treating HIV.