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NLM AIDSLINE

CD30-positive lymphoma in human T-cell leukaemia virus type 1 carrier without monoclonal integration of HTLV-1.




 

Br J Haematol. 1994 Oct;88(2):419-20. Unique Identifier : AIDSLINE

CD30, Ki-1 antigen, an activated T-cell antigen, is a member of the nerve growth factor receptor family. This antigen is expressed on the lymphoma cells of some adult T-cell leukaemia/lymphoma (ATL/L) patients and some patients with Epstein-Barr virus infection. CD30-positive large cell cutaneous T-cell lymphomas occasionally integrate a defective HTLV-1 provirus. We describe here an HTLV-1 carrier who developed Ki-1 lymphoma with no evidence of monoclonal integration of the HTLV-1 proviral sequence.

Blotting, Southern Carrier State/*VIROLOGY Case Report Human HTLV-I/*ISOLATION & PURIF HTLV-I Infections/*COMPLICATIONS Lymphoma, Large-Cell, Ki-1/COMPLICATIONS/*VIROLOGY Middle Age Proviruses/ISOLATION & PURIF Virus Integration JOURNAL ARTICLE



 




Information in this article was accurate in April 30, 1995. The state of the art may have changed since the publication date. This material is designed to support, not replace, the relationship that exists between you and your doctor. Always discuss treatment options with a doctor who specializes in treating HIV.