Resource Logo

Usefulness of bone marrow aspirate examination in HIV- infected patients.


Natl Conf Hum Retroviruses Relat Infect (1st). 1993 Dec 12-16;:142.

To determine the utility of bone marrow aspirate examination (BMAE) for the diagnosis of opportunistic infections and lymphoma in HIV-infected patients, we retrospectively reviewed the records of all patients undergoing diagnostic BMAE at one AIDS reference center in Madrid, Spain between April 1991 and June 1993. Specimens were examined cytologically and microbiologically for opportunistic pathogens or lymphoma. A total of 186 specimens have been analyzed. Suspicion of Mycobacterial 'granulomatous' images were recognized in 24% of cases, and positive Mycobacterial cultures were achieved in 44% of them Mycobacterium avium complex infections were three times more frequent than tuberculosis. Leishmania amastigotes were seen in 11% of cases, and Visceral leishmaniasis was confirmed in all of them. Lymphoma was suspected in 10%, and later confirmed in 80% of them. Fungal infections (histoplasmosis) were diagnosed in 2 (1%) of patients because BMAE was performed mostly for fever of unknown origin and/or non-explained cytopenia, we concluded that BMAE is a rapid and accurate method for diagnosing OI and lymphomas in HIV-infected patients.

Adult Aged Biliary Tract Diseases/*COMPLICATIONS Female Hepatitis, Viral, Human Human HIV Infections/*COMPLICATIONS Liver Diseases/*COMPLICATIONS Male Middle Age Prospective Studies Serology ABSTRACT


Information in this article was accurate in December 30, 1995. The state of the art may have changed since the publication date. This material is designed to support, not replace, the relationship that exists between you and your doctor. Always discuss treatment options with a doctor who specializes in treating HIV.