Ned Tijdschr Geneeskd. 1996 May 25;140(21):1119-22. Unique Identifier :
OBJECTIVE. To determine whether the low incidence of non-Hodgkin's
lymphoma (NHL) in Curacao has changed in comparison with the increase in
incidence in many western countries, and to investigate the role of the
HTLV-I infection that is endemic in the Caribbean area. DESIGN.
Retrospective. SETTING. Curacao, Netherlands Antilles. METHOD.
Retrospective file analysis in the only hospital in Curacao. RESULTS.
During the period 1987-1992, 31 patients had a histologically confirmed
diagnosis of NHL resulting in an annual incidence rate of 4.9/100,000
adults. There was a strong age-related increase in NHL incidence rate
(0.5 for patients < 30 years to 17.8 for patients > or = 70 years), with
a male to female ratio of I. (In the western world the incidence is
12-14, in the seventies it was 4.5 in Curacao.) Seven of 12 patients
(58%) tested were seropositive for HTLV-I. Median survival was 6 months,
despite conventional therapy. CONCLUSION. While HTLV-I infection can
often be demonstrated in NHL patients in Curacao, NHL incidence has
remained low over the past 25 years.
Adolescence Adult Aged Demography English Abstract Female Human
HTLV-I Infections/*EPIDEMIOLOGY Incidence Lymphoma,
Non-Hodgkin's/*EPIDEMIOLOGY Male Middle Age Netherlands
Antilles/EPIDEMIOLOGY Retrospective Studies Seroepidemiologic Methods