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NLM AIDSLINE

[Low incidence of non-Hodgkin lymphoma but high seroprevalence of HTLV-I in Curacao]




 

Ned Tijdschr Geneeskd. 1996 May 25;140(21):1119-22. Unique Identifier :

OBJECTIVE. To determine whether the low incidence of non-Hodgkin's lymphoma (NHL) in Curacao has changed in comparison with the increase in incidence in many western countries, and to investigate the role of the HTLV-I infection that is endemic in the Caribbean area. DESIGN. Retrospective. SETTING. Curacao, Netherlands Antilles. METHOD. Retrospective file analysis in the only hospital in Curacao. RESULTS. During the period 1987-1992, 31 patients had a histologically confirmed diagnosis of NHL resulting in an annual incidence rate of 4.9/100,000 adults. There was a strong age-related increase in NHL incidence rate (0.5 for patients < 30 years to 17.8 for patients > or = 70 years), with a male to female ratio of I. (In the western world the incidence is 12-14, in the seventies it was 4.5 in Curacao.) Seven of 12 patients (58%) tested were seropositive for HTLV-I. Median survival was 6 months, despite conventional therapy. CONCLUSION. While HTLV-I infection can often be demonstrated in NHL patients in Curacao, NHL incidence has remained low over the past 25 years.

Adolescence Adult Aged Demography English Abstract Female Human HTLV-I Infections/*EPIDEMIOLOGY Incidence Lymphoma, Non-Hodgkin's/*EPIDEMIOLOGY Male Middle Age Netherlands Antilles/EPIDEMIOLOGY Retrospective Studies Seroepidemiologic Methods JOURNAL ARTICLE



 




Information in this article was accurate in October 30, 1996. The state of the art may have changed since the publication date. This material is designed to support, not replace, the relationship that exists between you and your doctor. Always discuss treatment options with a doctor who specializes in treating HIV.