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Cytomegalovirus polyradiculopathy in HIV-infected patients.




 

J Gen Intern Med. 1996 Jan;11(1):47-9. Unique Identifier : AIDSLINE

Cytomegalovirus polyradiculopathy, a late complication of HIV infection, is characterized by lower extremity weakness, urinary retention, and sacral dysesthesias. We describe four patients (mean CD4 T-cell count = 25 cells/mm3) who developed this infectious cauda equina syndrome. The characteristic cerebrospinal fluid (CSF) findings, notably atypical for a viral infection, included polymorphonuclear leukocytosis (mean white blood cell count = 1512 cells/mm3, 72% polymorphonuclear leukocytes), elevated protein level (mean = 370 mg/dl), and hypoglycorrhacia (mean = 28 mg/dl). Physicians who treat patients with HIV should be familiar with this syndrome because early intervention, prior to microbiologic confirmation, provides the best hope for improving neurologic function.

Adult Antiviral Agents/THERAPEUTIC USE AIDS-Related Opportunistic Infections/DIAGNOSIS/DRUG THERAPY/ *PHYSIOPATHOLOGY Case Report Cytomegalovirus Infections/DIAGNOSIS/DRUG THERAPY/ *PHYSIOPATHOLOGY Ganciclovir/THERAPEUTIC USE Human Male Peripheral Nervous System Diseases/DRUG THERAPY/ETIOLOGY/ *VIROLOGY Polyradiculitis/DRUG THERAPY/ETIOLOGY/*VIROLOGY Prognosis JOURNAL ARTICLE



 




Information in this article was accurate in October 30, 1996. The state of the art may have changed since the publication date. This material is designed to support, not replace, the relationship that exists between you and your doctor. Always discuss treatment options with a doctor who specializes in treating HIV.