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The impact of changes in first AIDS-defining illnesses in Queensland 1985-1994 on survival.


Annu Conf Australas Soc HIV Med. 1995 Nov 16-19;7:84 (abstract no. 97).

The one and 2 year survival rates for patients with a diagnosis of AIDS increased rapidly between 1984 and 1987, and at a more modest rate since then. This increase is associated with the widely used phrase "now that patients are living longer...". Is there any evidence to suggest that patients are living longer, or rather, are they being diagnosed earlier? Two important effects may be of significance: i) the range of AIDS-defining illnesses is constantly increasing, which may affect life-expectancy: ii) the willingness of notification authorities to accept presumptive diagnoses of AIDS-defining illnesses may tend to earlier diagnosis, and therefore an apparent extension of life with AIDS. The Queensland HIV/AIDS database is an active, single database which is periodically updated through contact with medical personnel managing patients. We have examined the records of patients with a first AIDS defining illness over time, looking for changes in the diseases, whether presumptively or definitively diagnosed, looked at CD4 counts at the time of diagnosis, and, for those who have died, calculated life expectancy from diagnosis to death. Our results will show an increasing trend to presumptive diagnoses, a higher CD4+ count with presumptive diagnoses, and a longer time to death; these results suggest that AIDS-defining illnesses are being diagnosed earlier, and the apparent increase in survival may be due to this.

Acquired Immunodeficiency Syndrome/DIAGNOSIS/IMMUNOLOGY/ *MORTALITY CD4 Lymphocyte Count Databases, Factual Human Life Expectancy Queensland/EPIDEMIOLOGY Survival Rate Time Factors ABSTRACT


Information in this article was accurate in December 30, 1996. The state of the art may have changed since the publication date. This material is designed to support, not replace, the relationship that exists between you and your doctor. Always discuss treatment options with a doctor who specializes in treating HIV.