Clin Infect Dis. 1996 Feb;22(2):369-71. Unique Identifier : AIDSLINE
We reviewed the autopsy findings for the submandibular glands of 60
patients with AIDS who were autopsied at the George Washington
University Medical Center (Washington, DC) from 1982 to 1992.
AIDS-associated infections in the submandibular glands were compared
with those in the pancreas and lung. Cytomegalovirus intranuclear
inclusions were found in 10 cases, and Pneumocystis carinii infection
was found in one case. Disseminated mycobacterial and fungal infections
were not identified in the submandibular gland, even in the presence of
documented pancreatic and pulmonary infection (P < .05). Overall, the
major salivary glands of patients with AIDS are less frequently involved
with disseminated opportunistic infections than is either the lung or
the pancreas (P < .01 and P < .001, respectively).
AIDS-Related Opportunistic Infections/*MICROBIOLOGY/VIROLOGY Cohort
Studies Cytomegalovirus Infections/*VIROLOGY Female Human
Lung/MICROBIOLOGY/VIROLOGY Male Pancreas/MICROBIOLOGY/VIROLOGY
Pancreatic Diseases/MICROBIOLOGY/VIROLOGY Pneumocystis carinii
Infections/*MICROBIOLOGY Submandibular Gland/*MICROBIOLOGY/VIROLOGY
Submandibular Gland Diseases/*MICROBIOLOGY/VIROLOGY Support, U.S.
Gov't, P.H.S. JOURNAL ARTICLE