AIDS. 1996 Dec;10 Suppl 4:S19-23. Unique Identifier : AIDSLINE
OBJECTIVE: Funduscopy was compared with retinal photographs in the
documentation of progression of cytomegalovirus (CMV) retinitis.
SETTING: Clinical centres provided oral ganciclovir maintenance therapy
for AIDS patients with CMV retinitis inaccurately involved in randomized
trials of oral versus intravenous ganciclovir for maintenance therapy of
patients with newly diagnosed or previously treated CMV retinitis, in
North America, Europe and Australia. DESIGN: Serial retinal photographs
and funduscopy examinations were conducted at each patient visit in
order to detect progression of CMV retinitis during the course of oral
ganciclovir maintenance therapy. CONCLUSIONS: Retinal photography is the
most accurate for central lesions, funduscopy is preferable for diffuse
and peripheral lesions, and in the day-to-day management of patients,
the combined approach provides the most accurate information.
*Antiviral Agents/THERAPEUTIC USE *Fluorescein Angiography
*Ganciclovir/THERAPEUTIC USE *Ophthalmoscopy