AJNR Am J Neuroradiol. 1997 Oct;18(9):1721-5. Unique Identifier :
PURPOSE: To determine the factors that correspond to adenoidal
hypertrophy, often prominent in human immunodeficiency virus
HIV)-positive patients. METHODS: The sagittal T1-weighted MR images of
21 HIV-positive patients (age range, 25 to 50 years; mean, 37 years) and
21 healthy control subjects (age range, 24 to 55 years; mean, 35 years)
were reviewed blindly and independently by two radiologists who measured
the maximal dimension of the nasopharyngeal lymphoid tissue. Twenty-six
additional HIV-positive patients were combined with the original 21
HIV-positive patients, and the hematologic studies of these 47 patients
were compared with the adenoidal measurements to assess whether a
relationship existed between nasopharyngeal prominence and hematocrit,
white blood cell count, and CD4 count. RESULTS: Mean adenoidal width was
6.76 mm (SD, 5.82) in the HIV-positive population, but was only 3.36 mm
(SD, 2.48) in the age-matched control group. Age and HIV status
correlated with nasopharyngeal width measurements. No relationship
between adenoidal width and hematocrit, CD4 count, or white blood cell
count was evident. CONCLUSION: After correcting for age, we found that
adenoidal lymphoid tissue is more abundant in HIV-positive persons than
in control subjects. The hematologic ramifications of this finding
remain uncertain.
*Adenoids/PATHOLOGY *HIV Seropositivity/DIAGNOSIS *Magnetic Resonance
Imaging