interferon therapy for japanese hemophiliacs with chronic hepatitis c.

NLM AIDSLINE Interferon therapy for Japanese hemophiliacs with chronic hepatitis C. Miura T; Meguro T; Takayama S; Yamada K; Department of Pediatrics, Haga
March 30, 1998

Acta Paediatr Jpn. 1997 Oct;39(5):556-8. Unique Identifier : AIDSLINE Eight Japanese hemophiliacs with chronic hepatitis C (CHC) received interferon (IFN) therapy and four of them (50%) responded completely. Non-responders included 3 double-infected patients: 1 with hepatitis B virus (HBV) and 2 with human immunodeficiency virus-1 (HIV-1). In one of the patients with HIV-1 double infection, the absolute number of CD4+ lymphocytes decreased during IFN therapy. These findings suggest that hemophiliac patients with CHC can respond well to IFN therapy, but in patients who are double-infected with HBV and HIV-1, the indication of IFN therapy should be considered seriously. HIV-1 Hemophilia/COMPLICATIONS Hepatitis C/THERAPY Hepatitis, Chronic/THERAPY *Interferon-beta/THERAPEUTIC USE

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Information in this article was accurate in March 30, 1998. The state of the art may have changed since the publication date. This material is designed to support, not replace, the relationship that exists between you and your doctor. Always discuss treatment options with a doctor who specializes in treating HIV.