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Lymph node enlargement in HIV patients: diagnosis by fine-needle aspiration (FNA).


Int Conf AIDS. 1998;12:1014 (abstract no. 60073). Unique Identifier :

BACKGROUND: To establish the usefulness of the FNA biopsy in the clinical approach of peripheral adenopathies in AIDS patients, to determinate its role in further therapeutic interventions and to compare the frequency of different etiologies. METHODS: Patients selected for FNA fulfilled tile following criteries: all were adults with confirmed HIV infection and one or more persistent enlarged lymph nodes larger than 3 cm. for more than 30 days. Cytologic exam, Gram-stained, Grocott, Giemsa and Ziehl-Nielsen smears as well as bacterial, fungus and mycobacterial culture were performed from the aspirated material. RESULTS: Twenty-four FNA were analyzed. Forty-six percent (11/24) were localized lymph nodes, mainly in cervical region. The FNA was positive in 91.06% (22/24). There were 17 (77.3%) tuberculosis; 2 (9.1%) histoplasmosis; 1 (4.5%) cryptococcosis; 1 (4.5%) metastatic anaplasic cancer, and 2 (9.1%) non-Hodkin's lymphomas. One patient had two microorganisms in the same node (M. tuberculosis and H. capsulatum). CONCLUSION: FNA had a high diagnosis accuracy, with no false positive. The main agent isolated was M. tuberculosis, since peripheral tuberculous lymphadenopathy is the commonest form of extrapulmonary tuberculosis in HIV patients in our country. The possibility of two concurrent opportunistic agents in one single lymph node is highlighted. The low ratio of cancer in our series compared to infectious etiology is noted (1:6).

MEETING ABSTRACTS Adult AIDS-Related Opportunistic Infections/PATHOLOGY Biopsy, Needle Diagnosis, Differential Female Human Hyperplasia HIV Infections/*PATHOLOGY Lymph Nodes/*PATHOLOGY Lymphoma, AIDS-Related/PATHOLOGY Male Sensitivity and Specificity


Information in this article was accurate in December 30, 1998. The state of the art may have changed since the publication date. This material is designed to support, not replace, the relationship that exists between you and your doctor. Always discuss treatment options with a doctor who specializes in treating HIV.