Unique Identifier : AIDSLINE MED/99004789
OBJECTIVE: To examine the impact of the time period from first positive
HIV test to AIDS diagnosis and other variables on survival after AIDS
diagnosis. MATERIALS AND METHODS: All adult AIDS patients diagnosed and
reported to the national surveillance unit in Denmark in the period 1980
through June 1995. RESULTS: A total of 1745 patients was diagnosed in
the period, and for 1631 (93.5%) the date of first positive HIV test was
known. The median interval between this test and AIDS diagnosis was 912
d. Overall, 473 patients (29.0%) were found to be HIV-positive close to
the AIDS diagnosis (< or = 4 months). The time interval between first
positive HIV test and AIDS diagnosis varied by transmission categories.
Patients older than 40 y had a higher mortality than younger patients.
Patients infected by blood products had the highest mortality. The
survival time was shortest for patients presenting with HIV-wasting or
HIV-encephalopathy or with > or = 1 AIDS-defining disease. The time
interval between first positive HIV test and AIDS diagnosis had no
impact on survival. CONCLUSION: No association was found between
survival time and the time interval between first positive HIV test and
AIDS diagnosis. Older age and transmission by blood or blood products
were associated with shorter survival from AIDS diagnosis.
JOURNAL ARTICLE Acquired Immunodeficiency Syndrome/*MORTALITY Adult
Denmark/EPIDEMIOLOGY Female Human *HIV
Seropositivity/MORTALITY/TRANSMISSION Male Statistics, Nonparametric