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Extensive impairment of triazolam and alprazolam clearance by short-term low-dose ritonavir: the clinical dilemma of concurrent inhibition and induction [editorial]




 

J Clin Psychopharmacol. 1999 Aug;19(4):293-6. Unique Identifier :

EDITORIAL REVIEW REVIEW, TUTORIAL JOURNAL ARTICLE Acquired Immunodeficiency Syndrome/*DRUG THERAPY/ENZYMOLOGY Alprazolam/*PHARMACOKINETICS Animal Cytochrome P-450/*ANTAGONISTS & INHIB/BLOOD Drug Interactions Enzyme Induction/DRUG EFFECTS Human HIV Protease Inhibitors/ADMINISTRATION & DOSAGE/*ADVERSE EFFECTS Metabolic Clearance Rate/DRUG EFFECTS Microsomes, Liver/DRUG EFFECTS/ENZYMOLOGY Oxidoreductases, N-Demethylating/*ANTAGONISTS & INHIB/BLOOD Ritonavir/ADMINISTRATION & DOSAGE/*ADVERSE EFFECTS Sedatives, Nonbarbiturate/*PHARMACOKINETICS Support, U.S. Gov't, P.H.S. Triazolam/*PHARMACOKINETICS



 




Information in this article was accurate in December 30, 1999. The state of the art may have changed since the publication date. This material is designed to support, not replace, the relationship that exists between you and your doctor. Always discuss treatment options with a doctor who specializes in treating HIV.