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NLM AIDSLINE

Study of the aetiologic agents of meningitis in Kumasi, Ghana, with special reference to Cryptococcal neoformans.




 

East Afr Med J. 1998 Sep;75(9):516-9. Unique Identifier : AIDSLINE

OBJECTIVE: To evaluate the importance of Cryptococcus neoformans, an opportunistic in meningitis, in healthy and HIV infected patients in Kumasi, Ghana. DESIGN: A prospective study; isolating the aetiologic agents of meningitis from cerebrospinal fluid (CSF) using standard methods. SETTING: Kumasi city, Ashanti region of central Ghana. SUBJECTS: One thousand five hundred and seventy patients suspected of meningitis, including 28 HIV infected and AIDS patients. MAIN OUTCOME MEASURE: The pattern and distribution of the main etiologic agents of meningitis in Kumasi, Ghana shown. RESULTS: Of the 1570 CSF samples examined, 1256 (80%) showed no abnormality. Of the 314 (20%) with abnormalities, 147 were bacterial, and 167 diagnosed aseptic. No cryptococcal cells were found. CONCLUSION: There is a paucity of cryptococcal meningitis in Kumasi, Ghana, and it is not recommended to screen routinely for the fungus in meningitis investigations.

JOURNAL ARTICLE Adolescence Adult AIDS-Related Opportunistic Infections/CEREBROSPINAL FLUID/ EPIDEMIOLOGY/*MICROBIOLOGY Child Child, Preschool Cryptococcosis/CEREBROSPINAL FLUID/EPIDEMIOLOGY/*MICROBIOLOGY *Cryptococcus neoformans Female Ghana/EPIDEMIOLOGY Human Infant Male Mass Screening Meningitis, Aseptic/CEREBROSPINAL FLUID/EPIDEMIOLOGY/ *MICROBIOLOGY Meningitis, Bacterial/CEREBROSPINAL FLUID/EPIDEMIOLOGY/ *MICROBIOLOGY Meningitis, Fungal/CEREBROSPINAL FLUID/EPIDEMIOLOGY/*MICROBIOLOGY Prospective Studies Urban Health



 




Information in this article was accurate in December 30, 1999. The state of the art may have changed since the publication date. This material is designed to support, not replace, the relationship that exists between you and your doctor. Always discuss treatment options with a doctor who specializes in treating HIV.