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CDC HIV/AIDS/Viral Hepatitis/STD/TB Prevention News Update

UNITED STATES: Hepatitis A Vaccination Coverage Among Adolescents in the United States


Pediatrics doi:10.1542/peds.2011-2197 (01.23.12) - Friday,

"Hepatitis A infection causes severe disease in adolescents and adults," the authors wrote in their introduction. CDC's Advisory Committee on Immunization Practices instituted incremental recommendations for hepatitis A vaccination (HepA) at two years of age based on risk in 1996; in selected states in 1999; and universally at one year of age, with vaccination through age 18 based on risk or desire for protection, in 2006. In the current study, the team assessed adolescent HepA coverage in the United States and factors independently associated with receiving the vaccine.

To determine =1- and =2-dose HepA coverage among youths ages 13-17, data from the 2009 National Immunization Survey-Teen (n=20,066) were analyzed. The researchers used bivariate and multivariable analyses to test associations between HepA initiation and sociodemographic characteristics stratified by state groups: group 1, universal child vaccination since 1999; group 2, consideration for child vaccination since 1999; and group 3, universal child vaccination at one year of age since 2006.

The results showed that national 1-dose HepA coverage among adolescents was 42 percent in 2009, with 70 percent of vacinees completing the 2-dose series. One-dose coverage was 74.3 percent among states in group 1; 54 percent among states in group 2; and 27.8 percent among states in group 3.

"The adjusted prevalence ratios of vaccination initiation were highest for states with a vaccination requirement and for adolescents whose providers recommended HepA," the authors found. "HepA coverage was low among most adolescents in the United States in 2009, leaving a large population susceptible to hepatitis A infection maturing into adulthood."


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