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Inflammation, Immune Activation, and HIV




 

Inflammation is a broad term for what happens in the body when the immune system is activated to counter a threat. A healthy immune response is key to good health, but ongoing immune activation
and inflammation due to a persistent threat such as chronic HIV infection can lead to many different problems throughout the body.

Among people with HIV, combination antiretroviral therapy (ART) has dramatically reduced the risk of AIDS-defining opportunistic illnesses (OIs) and mortality directly related to immune suppression. But as HIV positive people survive longer, they are at increased risk for a variety of non-AIDS conditions even when their CD4 cell counts are high.

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Copyright © 2010 -BETA, Publisher. All rights reserved to the San Francisco AIDS Foundation. Reproduced by permission. Reproduction of this article (other than one copy for personal reference) must be cleared through BETA: PO Box 426182, San Francisco, CA 94142-6182. Tel: 415 487 8060 Fax: 415 487 8069 San Francisco AIDS Foundation, Mail SFAF..

Information in this article was accurate in March 10, 2010. The state of the art may have changed since the publication date. This material is designed to support, not replace, the relationship that exists between you and your doctor. Always discuss treatment options with a doctor who specializes in treating HIV.