Treatment Review No. 20; November 1995
Kaposi's sarcoma is a kind of cancer that can cause lesions or
marks on the skin. It can sometimes also spread inside the
body. Although no treatment is 100% effective at controlling
this cancer, some treatments produce benefits. NYU Medical
Center is studying a drug which is derived from vitamin A . The
drug, 9-cis-retinoic acid, is similar to Retin-A, the drug
commonly used for acne (pimples). 9-cis-retinoic acid is a
topical cream that is applied directly to KS lesions. It will
be given to all participants enrolled in the study.
Participants will apply the cream to their lesions twice a day
for the first two weeks and then four times a day for the next
two weeks. If the cream is effective, participants may be
permitted to remain on the study drug. To be eligible for this
trial, you cannot have systemic (inside your body) KS or be
taking any other treatments for KS.