2012 JUN 18 (NewsRx) -- By a News Reporter-Staff News Editor at AIDS Weekly -- Investigators publish new report on HIV/AIDS. According to news reporting from Portsmouth, Virginia, by NewsRx journalists, researchers stated "The well-described biologic and epidemiologic associations of syphilis and HIV are particularly relevant to the military, as service members are young and at risk for sexually transmitted infections. We therefore used the results of serial serologic testing to determine the prevalence, incidence, and risk factors for incident syphilis in a cohort of HIV-infected Department of Defense beneficiaries."
The news correspondents obtained a quote from the research by the authors from United States Navy, "Participants with a positive nontreponemal test at HIV diagnosis that was confirmed on treponemal testing were categorized as prevalent cases, and participants with an initial negative nontreponemal test who subsequently developed a confirmed positive nontreponemal test were categorized as incident cases. At HIV diagnosis, the prevalence of syphilis was 5.8% (n = 202). A total of 4239 participants contributed 27,192 person-years (PY) to the incidence analysis and 347 (8%) developed syphilis (rate, 1.3/100 PY; [1.1, 1.4]). Syphilis incidence was highest during the calendar years 2006 to 2009 (2.5/100 PY; [2.0, 2.9]). In multivariate analyses, younger age (per 10 year increase hazard ratio [HR], 0.8; [0.8-0.9]), male gender (HR, 5.6; [2.3-13.7]), non-European-American ethnicity (African-American HR, 3.2; [2.5-4.2]; Hispanic HR, 1.9; [1.2-3.0]), and history of hepatitis B (HR, 1.5; [1.2-1.9]) or gonorrhea (HR, 1.4; [1.1-1.8]) were associated with syphilis. The significant burden of disease both at and after HIV diagnosis, observed in this cohort, suggests that the cost-effectiveness of extending syphilis screening to at-risk military members should be assessed."
According to the news reporters, the researchers concluded: "In addition, HIV-infected persons continue to acquire syphilis, emphasizing the continued importance of prevention for positive programs."
For more information on this research see: Results of a 25-Year Longitudinal Analysis of the Serologic Incidence of Syphilis in a Cohort of HIV-Infected Patients With Unrestricted Access to Care. Sexually Transmitted Diseases, 2012;39(6):440-448. Sexually Transmitted Diseases can be contacted at: Lippincott Williams & Wilkins, 530 Walnut St, Philadelphia, PA 19106-3621, USA. (Lippincott Williams and Wilkins - www.lww.com; Sexually Transmitted Diseases - journals.lww.com/stdjournal/pages/default.aspx)
Our news journalists report that additional information may be obtained by contacting A. Ganesan, USN, Medical Center Portsmouth, Portsmouth, VA, United States (see also HIV/AIDS).
Keywords for this news article include: Virginia, HIV/AIDS, Syphilis, Aerospace, Portsmouth, RNA Viruses, Retroviridae, United States, HIV Infections, Infectious Disease, Vertebrate Viruses, Primate Lentiviruses, Department Of Defense, Opportunistic Infections, North and Central America, Bacterial Infections and Mycoses, Viral Sexually Transmitted Diseases
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