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CDC HIV/AIDS/Viral Hepatitis/STD/TB Prevention News Update

UNITED STATES: Home Field Advantage: Intravaginal Immunization May Help Protect Against Infection


Medical Xpress (11.12.12) Aids Weekly Plus

Researchers led by John Schiller at the National Cancer Institute have published a study exploring the immune response to intravaginal immunization in mice infected with a strain of the HPV virus carrying a certain antigen. The researchers found that intravaginal immunization significantly increased the number of immune cells present in the vaginal mucosa as compared to a general immune system booster. The results show that area-specific vaccination enhances the local immune system response and may be helpful in developing STD vaccines. The study titled,"Intravaginal Immunization with HPV Vectors Induces Tissue-Resident CD8+ T cell Responses" is published online in the Journal of Clinical Investigation (2012; doi:10.1172/JCI63287).


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Information in this article was accurate in November 14, 2012. The state of the art may have changed since the publication date. This material is designed to support, not replace, the relationship that exists between you and your doctor. Always discuss treatment options with a doctor who specializes in treating HIV.