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Report Summarizes HIV/AIDS and Tuberculosis Study Findings from Walter Reed Army Institute of Research


2013 JUL 1 (NewsRx) -- By a News Reporter-Staff News Editor at AIDS Weekly -- Researchers detail new data in Opportunistic Infections. According to news reporting out of Silver Spring, Maryland, by NewsRx editors, research stated, "President's Emergency Plan for AIDS Relief (PEPFAR) has been criticized for its vertical or 'stove-piping' structure, with resources targeting a specific disease rather than working to strengthen the underlying health system. This study aimed to evaluate whether PEPFAR activities were associated with system-wide improvements in both proximal and distal indicators of health systems strengthening."

Our news journalists obtained a quote from the research from the Walter Reed Army Institute of Research, "The World Bank database provided 12 indicators of health systems strengthening that were analyzed for their relationship to PEPFAR. Poisson and linear regression models were used to estimate the time trend. We evaluated the PEPFAR impact on health outcomes by comparing the time trend in each of the above indicators between 2 time periods: from 1995 to 2002 (pre-PEPFAR) and from 2004 to 2010 (during PEPFAR). PEPFAR activities showed strong and statistically significant associations with improvements in proximal indicators of health systems strengthening, those related directly to HIV, specifically life expectancy (P = 0.003) and tuberculosis incidence, prevalence, and mortality (P < 0.0001). There were nonsignificant associations between PEPFAR and improvements in distal indicators of health systems strengthening, namely infant mortality and under 5 child mortality. The progressive scale-up of PEPFAR-supported activities was associated with consistent improvements in proximal indicators of health systems strengthening. It was also associated with improvements in broader measures of health system strength, most clearly life expectancy."

According to the news editors, the research concluded: "Given the limited number of health measures available for this type of analysis, more data must be collected for other indicators to evaluate the effectiveness of the many multibillion dollar global health initiatives."

For more information on this research see: An Evaluation of the President's Emergency Plan for AIDS Relief Effect on Health Systems Strengthening in Sub-Saharan Africa. Jaids-Journal of Acquired Immune Deficiency Syndromes, 2013;62(4):471-479. Jaids-Journal of Acquired Immune Deficiency Syndromes can be contacted at: Lippincott Williams & Wilkins, 530 Walnut St, Philadelphia, PA 19106-3621, USA (see also Opportunistic Infections).

Our news journalists report that additional information may be obtained by contacting R.L. Cohen, Walter Reed Army Inst Res, Military HIV Res Program, Silver Spring, MD 20910, United States.

Keywords for this news article include: Maryland, Tuberculosis, Silver Spring, United States, Opportunistic Infections, North and Central America

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Information in this article was accurate in July 1, 2013. The state of the art may have changed since the publication date. This material is designed to support, not replace, the relationship that exists between you and your doctor. Always discuss treatment options with a doctor who specializes in treating HIV.