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Findings from National Institute of Infectious Diseases Broaden Understanding of HIV/AIDS


2013 NOV 25 (NewsRx) -- By a News Reporter-Staff News Editor at AIDS Weekly -- Current study results on Immune System Diseases and Conditions have been published. According to news reporting originating from Rome, Italy, by NewsRx correspondents, research stated, "Radiation recall dermatitis is an acute, rare skin reaction confined to previously irradiated areas that can be triggered by chemotherapeutic drugs (generally doxorubicin and taxanes), which are administrated after radiotherapy. We describe this case report to discuss the timing of the different choice of treatments of progressive Kaposis's sarcoma (KS) disease."

Our news editors obtained a quote from the research from the National Institute of Infectious Diseases, "KS, the neoplastic disease associated with HHV-8 infection, is still the most commonly diagnosed malignancy in HIV-1 patients, even if its incidence dramatically declined in the highly active antiretroviral therapy (HAART) era. The cutaneous form of disease generally improves with HAART alone or in association with local treatment (cryotherapy, radiotherapy, intralesion chemotherapy), whereas disseminated and/or progressive disease needs to be treated with systemic chemotherapy. In selected patients with progressive disease, systemic and local therapeutic options should be associated. We report a case of a 30-year-old HIV-1-positive man, affected by epidemic cutaneous and mucosal KS, who received several cycles of chemotherapy in succession with radiotherapy and other chemotherapy treatments for disease progression."

According to the news editors, the research concluded: "After 7months, the end of the last rechallenge with chemotherapy, the patient presented cutaneous painful and ulcerated lesions on the same skin areas previously irradiated."

For more information on this research see: Radiation recall dermatitis in course of epidemic Kaposi's sarcoma. Dermatologic Therapy, 2013;26(5):424-427. Dermatologic Therapy can be contacted at: Wiley-Blackwell, 111 River St, Hoboken 07030-5774, NJ, USA. (Wiley-Blackwell -; Dermatologic Therapy -

The news editors report that additional information may be obtained by contacting A. Latini, Natl Inst Infect Dis, Rome, Italy. Additional authors for this research include C. Cota, V. Ferraresi, P. Cordiali-Fei, M. Giuliani, E. Trento, M. Zaccarelli, A. Bonadies, A. Di Carlo and G. Palamara (see also Immune System Diseases and Conditions).

Keywords for this news article include: Rome, Italy, Europe, Dermatitis, Cryotherapy, Dermatology, Chemotherapy, Radiotherapy, Skin Diseases, Medical Devices, Combination Drug Therapy, Skin and Connective Tissue Diseases, Highly Active Antiretroviral Therapy, Immune System Diseases and Conditions

Our reports deliver fact-based news of research and discoveries from around the world. Copyright 2013, NewsRx LLC


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Information in this article was accurate in November 25, 2013. The state of the art may have changed since the publication date. This material is designed to support, not replace, the relationship that exists between you and your doctor. Always discuss treatment options with a doctor who specializes in treating HIV.